Fig. 1.

Model fits with empirical kinetic data and predicted time to cure. (A) Best curve fits of CE (gray line) and VE (black line) models with observed data; (B) Based on the VE model, which yields a better fit than the CE model, virus is predicted to be eradicated from the circulation by 175 days (25 weeks) and infected cells by 238 days (34 weeks).Not detectable HCV RNA , i.e., <12 IU/ml (gray filled triangles), measured during therapy, were arbitrarily set to 0.3 log IU/ml. Estimated viral and host parameters are shown in Table 1.