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. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: Osteoarthritis Cartilage. 2014 Nov 11;23(2):266–274. doi: 10.1016/j.joca.2014.11.006

Figure 4.

Figure 4

The effects of IGF-1 (100 ng/ml) and Dex (100 nM) on bovine chondrocyte gene expression after 4-day treatment with IL-1α (1 ng/ml). For each condition, 6 cartilage disks from the same animal were pooled for mRNA extraction; n = 5 animals. Gene expression levels were normalized to that of the 18S gene and then normalized to the untreated control condition which had an expression level = 1 (dotted line). Data are presented as mean ± 95% confidence interval, * vs. untreated control (p<0.001); # vs. IL-1α alone (p<0.001); $:p < 0.001.