Table 2.

IG loci genomic feature statistics and SNP density comparisons

	IGHV	IGLV	IGKV
Genomic feature
Total bp Comp	834 802	760 133	858 805
Total SNPs	2897	854	519
Seg Dup fraction (⩾90%)	0.377	0.278	0.304 (0.887)1
Seg Dup fraction (90–95%)	0.138	0.2	0.287 (0.287)1
Seg Dup fraction (95–100%)	0.288	0.146	0.051 (0.826)1
Repeat coverage	0.534	0.433	0.469
Number of F or ORF V genesa	42	37	44
SNP density
Locus-wide	0.0035	0.0011	0.0006
F/ORF V gene	0.0039	0.0015	0.0017
Non Seg Dups	0.0031	0.0012	0.0004 (0.0004)b
Seg Dups	0.0042	0.001	0.001 (0.0006)b
Seg Dups (90–95%)	0.0033	0.001	0.001 (0.001)b
Seg Dups (95–100%)	0.0045	0.0014	0.001 (0.0006)b
Repeats	0.0031	0.0011	0.0006

Abbreviations: IG, immunoglobulin; ORF, open reading frame; SNP, single-nucleotide polymorphism.

^aOnly those genes found in the CH17 and assemblies generated by Kawasaki et al.^15,23 and Matsuda et al.³⁸ were considered, excluding duplications and deletions described in IGHV.⁶

^bCalculations in parentheses include inverted segmental duplications between the proximal and distal units of IGKV.