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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Genes Immun. 2014 Nov 20;16(1):89–98. doi: 10.1038/gene.2014.65

Figure 5.

Figure 5

MIR181A1B1 and MIR181A2B2 TSS. RNA was harvested from the NK cells of two (MIR181A2B2) or three (MIR181A1B1) subjects and 5’RACE was performed. Underlined nt denote the 5’ end of RACE clones, with major TSS indicated by larger font size. Boxes enclose potential Initiator elements (consensus sequence, YYANWYY). Transcription direction is left to right. A. Chr1:198 906 606 - 519 depicting MIR181A1B1 TSS. The number of 5’RACE clones found (underlined letters from left to right) were 2 (A), 16 (A), 9 (T), 15 (A). The circled “A” shows the 5’ end of the previously reported NR_040073 transcript. B. Chr9:127 420 695 – 824 depicting MIR181A2B2 TSS. The number of 5’RACE clones found (underlined letters from left to right) were 1 (A), 1 (G), 1 (G), 11 (A), 17 (A), and 1 (T). The underlined and circled “G” refers to the beginning of the previously reported NR_038975 transcript, which coincides with the start of a 5’RACE clone. For each sequence, an “ATG” that was modified to “TTG” in the luciferase reporter plasmids is shown as bold letters.