Table 2. Relationship of jSLE demographics and disease features to HRQOL and to presence of obesityŦ.
Outcomes¶ | HRQOL | Presenceof obesity | ||
---|---|---|---|---|
Predictors | Beta-coefficient or slope | P-value* | Odds ratio | P-value** |
Age (< 12 years) | 0.1 | NS | 0.6 | NS |
Gender: Female | 0.2 | NS | 0.8 | NS |
Ethnicity: Hispanic | 1.5 | NS | 1.3 | NS |
Race: African American | -8.8 | 0.01 | 2.3 | 0.01 |
At least moderate disease activity (Total SLEDAI score > 4) | -5.5 | 0.02 | 1.4 | NS |
More than minimal disease damage (Total SLICC score > 0) | -2.5 | NS | 0.6 | NS |
Current low daily prednisone dose (< 0.2 mg/kg/day and < 5 mg/day) | 5.4 | 0.03 | 0.4 | NS |
Current immunosuppressive use | 0.2 | NS | 1.2 | NS |
Current use of intravenous methylprednisolone pulses | 1.7 | NS | 0.6 | NS |
Legend:
For PedsQL Generic Core Scale. Results similar to summary scores of PedsQL-Rheumatology Module and CHQ. For the PedsQL-Rheumatology Module (self- report), gender is also significant
Outcomes of univariate analyses are: A) summary scores of HRQOL measures (shown here: PedsQL-Generic Core Scale parent-report) and B) presence of obesity
P-value from univariate mixed effects analyses to evaluate association of covariate of interest to outcome (i.e. domains scores of HRQOL measures)
P-value from logistic regression to evaluate association of covariate to presence of obesity