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. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: Cancer. 2014 Sep 23;121(3):467–475. doi: 10.1002/cncr.29065

Table 3.

Results of Cox proportional hazards models of overall survival and competing risks regression models of local failure and distant failure according to mode of local control. Patients treated with definitive surgery form the reference group in all models and therefore have hazard ratios of 1.

Covariates in
Addition to Mode
of Local Control		 Hazard Ratio for
Death for
Patients Treated
with Definitive
Radiation (95%
Confidence
Interval)		 Hazard Ratio for
Death for
Patients Treated
with Surgery
plus Radiation
(95% Confidence
Interval)		 Hazard Ratio for
Distant Failure
for Patients
Treated with
Definitive
Radiation (95%
Confidence
Interval)		 Hazard Ratio for
Distant Failure
for Patients
Treated with
Surgery plus
Radiation (95%
Confidence
Interval)		 Hazard Ratio for
Local Failure for
Patients Treated
with Definitive
Radiation (95%
Confidence
Interval)		 Hazard Ratio for
Local Failure for
Patients Treated
with Surgery
plus Radiation
(95% Confidence
Interval)
None (unadjusted models) 1.84 (1.19 – 2.85)
p = 0.006		 1.75 (1.10 – 2.76)
p = 0.02		 1.41 (0.89 – 2.22)
p = 0.14		 1.22 (0.76 – 1.97)
p = 0.40		 2.57 (1.37 – 4.83)
p = 0.003		 1.33 (0.62 – 2.89)
p = 0.47
Surgical and radiation propensity scores 1.37 (0.83 – 2.26)
p = 0.21		 1.39 (0.86 – 2.25)
p = 0.18		 1.13 (0.70 – 1.84)
p = 0.61		 0.98 (0.60 – 1.58)
p = 0.93		 2.41 (1.24 – 4.68)
p = 0.01		 1.04 (0.46 – 2.35)
p = 0.93
Surgical and radiation propensity scores, age, and tumor site 1.37 (0.84 – 2.23)
p = 0.21		 1.36 (0.85 – 2.20)
p = 0.20		 1.11 (0.69 – 1.78)
p = 0.66		 0.99 (0.61 – 1.60)
p = 0.96		 2.33 (1.17 – 4.62)
p = 0.02		 0.97 (0.41 – 2.29)
p = 0.95
Surgical and radiation propensity scores, age, tumor site, and clinical trial 1.38 (0.84 – 2.27)
p = 0.20		 1.35 (0.83 – 2.19)
p = 0.22		 1.15 (0.71 – 1.86)
p = 0.57		 0.99 (0.61 – 1.61)
p = 0.96		 2.39 (1.20 – 4.74)
p = 0.01		 0.96 (0.40 – 2.27)
p = 0.92
Surgical and radiation propensity scores, age, tumor site, and tumor size 1.65 (0.82 – 3.32)
p = 0.16		 1.58 (0.75 – 3.30)
p = 0.23		 1.27 (0.60 – 2.65)
p = 0.50		 1.45 (0.71 – 2.95)
p = 0.33		 4.28 (1.63 – 11.24)
p = 0.003		 1.43 (0.26 – 7.92)
p = 0.67
Age, tumor site, and year of diagnosis 1.38 (0.84 – 2.27)
p = 0.20		 1.34 (0.83 – 2.18)
p = 0.23		 1.16 (0.71 – 1.89)
p = 0.55		 0.97 (0.60 – 1.58)
p = 0.91		 2.39 (1.17 – 4.88)
p = 0.02		 1.01 (0.43 – 2.38)
p = 0.98
Age, tumor site, and clinical trial 1.39 (0.85 – 2.28)
p = 0.19		 1.35 (0.84 – 2.19)
p = 0.22		 1.16 (0.71 – 1.90)
p = 0.54		 0.98 (0.61 – 1.60)
p = 0.95		 2.32 (1.14 – 4.70)
p = 0.02		 1.02 (0.43 – 2.39)
p = 0.96
Age, tumor site, year of diagnosis, and tumor size 1.61 (0.80 – 3.26)
p = 0.18		 1.50 (0.72 – 3.15)
p = 0.28		 1.26 (0.59 – 2.71)
p = 0.52		 1.45 (0.71 – 2.94)
p = 0.33		 4.17 (1.53 – 11.39)
p = 0.006		 1.43 (0.26 – 7.92)
p = 0.68