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. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: Osteoarthritis Cartilage. 2014 Nov 15;23(2):300–307. doi: 10.1016/j.joca.2014.11.009

Figure 2.

Figure 2

Adiabatic T1ρ relaxation time map (panel A) obtained from the distal femur of a goat 2 weeks post operatively with the affected area enlarged, demonstrating mildly increased relaxation time in the area corresponding with the area of decreased proteoglycan content in panel B. Arrowhead indicates minor alterations in the advancement of the ossification front. Photomicrograph of a safranin-O stained section (panel B) obtained from the axial aspect of the medial femoral condyle of the same specimen (scale bar = 500 m). The surgical incision is partially healed (black arrows in panel A). Faint staining marked by a dotted line indicates decreased proteoglycan content in the area of cartilage necrosis. Panel C depicts high magnification image (scale bar = 50 m) of the area marked by the black box in panel B in a hematoxylin and eosin stained ssection. Chondrocytes to the right of the dotted diagonal line are necrotic, characterized by pyknotic nuclei and shrinkage.