Table 1.

Histological and MRI findings obtained from eight goat kids after interruption of the vascular supply to portions of the distal femur.

		Goat age at the time of euthanasia
		1 week	2 week	3 week	4 week	5 week	6 week#	9 week	10 week
Incision	Original size (mm)	~3 × 4	~3 × 4	5 × 5	~3 × 4	5 × 5	~3 × 4	5 × 5	~3 × 4
	Healing	No	Deep portion is forming granulation tissue	Deep ~50% is healed	Deep ~75% is healed	Deep ~90% is healed	Deep portion is forming granulation tissue	100% healed	100% healed
Cartilage canals		Necrosis distal to incision	Necrosis in axial ~50% of condyle	Absent in axial ~50% of condyle	Absent in axial ~20% of condyle	Absent in axial ~50% of condyle	Absent in axial ~50% of condyle	Low numbers in abaxial 50% of condyle	Absent or chondrified throughout
Chondrocyte	Extent of necrosis	Adjacent to incision	1.9 mm2 area in AECC	1.8 mm2 area in AECC	0.5 mm2 area in AECC	1.2 mm2 area in AECC	Not apparent	5.3 mm2 area a ossification front	0.6 mm2 area in subchondral bone
	Morphology	Shrinkage, pyknosis	Shrinkage, pyknosis	Shrinkage, pyknosis	Shrinkage, pyknosis	Shrinkage, pyknosis	Normal	Shrinkage, pyknosis	Shrinkage, pyknosis
	ECM$ staining	Retained	Mildly decreased	Markedly decreased	Mildly decreased	Markedly decreased	Retained	Markedly decreased	Nearly absent
T1rho relaxation time in necrotic cartilage		N/A*	Mildly increased (~250 ms)	Moderately increased (~300 ms)	No changes noted (~150 ms)	Markedly increased (~350 ms)	No changes noted (~150 ms)	Markedly increased (~350 ms)	Mildly increased (~250 ms)
OC classification		N/A	OC latens	OC latens	OC latens	OC latens	N/A	OC manifesta	Healing OC manifesta

^#In the 6-week-old goat the incision into the articular-epiphyseal cartilage-complex was created too superficially relative to the rest of the animals.

^$ECM = extracellular matrix

^*MRI study missed the area of lesion