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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Kidney Int. 2014 Jul 23;87(2):409–416. doi: 10.1038/ki.2014.261

Table 2.

Clinical outcomes and complications

Rituximab
N=25
No Rituximab
N=25
p value
DSA Rebound <2 weeks post-transplant 0.77
No. patients 9 (36%) 11 (44%)
Strength of Rebound: FCXM+ 4 (16%) 5 (20%)
FCXM−, DSA+ 5 (20%) 6 (24%)

DSA Persistence at 1 year: No. patients 13 10 0.57
  class I 4 6
  class II 5 3
  class I & II 4 1

Serum Creatinine (mean ± SD)
1 year 1.10 ± 0.30 1.26 ± 0.39 0.21
2 year 1.07 ± 0.22 1.28 ± 0.53 0.10

Infections ≤ 1 year No. patients 11 7 0.38
    Bacterial No. infections 15 6
    Viral 10 4
    Fungal 2 0
Total infections 27 10 0.08

Acute rejection1 ≤ 3 months No. patients 19 14 0.23
  CMR No. episodes 8 2
  Subclinical CMR 4 3
  Total 12 5
  AMR 3 4
  Subclinical AMR 1 2
  Total 4 6
  Mixed CMR & AMR 2 2
  Subclinical mixed 5 2
  Total 7 4

Transplant glomerulopathy
No. Patients (< 2 years) 4 2 0.17
1

Biopsy proven cell-mediated (CMR) and/or antibody-mediated (AMR) rejection or transplant glomerulopathy using updated Banff 97 criteria (5356)