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Rapid seroprotection against hepatitis B following the first dose of a Pre-S1/Pre-S2/S vaccine. Comparison of seroprotection (%), after one and two doses of 10 μg/1.0 ml of Sci-B-Vac (n = 10; shaded bars) and 20 μg/ml Engerix-B® (n = 8; white bars). Arrows reflect time of immunization. Reproduced by permission from Ref. [37]
