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Dose-dependent effects of mipomersen as a single agent on (a) apoB and (b) LDL cholesterol in patients with mild to moderate hyperlipidemia. Patients (N = 50) were treated for 13 weeks with mipomersen at a dose of 50–400 mg, or placebo [34]. Data presented are the median percentage change from baseline from day 1 to day 175. apoB apolipoprotein B, LDL low-density lipoprotein
