Skip to main content
. 2015 Feb;185(2):536–549. doi: 10.1016/j.ajpath.2014.10.022

Figure 3.

Figure 3

Dynamin-like protein 1 (Dlp1) expression is decreased in neurons and astrocytes in the frontal cortex of Parkinson disease (PD) patients. A: Fluorescent staining of Dlp1 (green) and mitogen-activated protein (MAP) 2 (red) in frontal cortex of control and PD patients. B: Quantification of Dlp1 intensity in neurons from control (N = 6 cases, 357 cells) and PD patients (N = 6 cases, 385 cells). C: Fluorescent staining of Dlp1 and glial fibrillary acidic protein (GFAP; red) in frontal cortex from control and PD patients. Arrows point at Dlp1 and GFAP colocalization. D: Quantification of Dlp1 intensity in astrocytes from control (N = 6 cases, 230 cells) and PD patients (N = 6 cases, 229 cells). Data are presented as means ± SEM. ∗∗∗P < 0.001 by two-sided unpaired t-test. Scale bar = 20 μm (A and C). Ctx, cortex.