Figure 2.

Forskolin administration attenuates renal pathology after the infection. A: Representative images of hematoxylin and eosin–stained kidneys from the control and forskolin-treated mice show renal histological changes including cellular infiltration, bacterial patchiness, abscess, and tubule destruction (arrows). B: Histologic scores in the control (black dots) and forskolin-treated (white dots) mice. Each dot represents a single animal; horizontal lines represent the means of renal pathological scores. ^∗P < 0.05, ^∗∗P < 0.01, Mann-Whitney test. Original magnification, ×100. Fsk, forskolin.