Table 2.
Longitudinal data: Odds ratio (OR) for generalized joint hypermobility (GJH), being a predictive factor for pain (arthralgia) development
| Outcome a | Univariate b analysis | Multivariable analysis | ||
|---|---|---|---|---|
| Arthralgia (n = 12) | Non-arthralgia (n = 288) | OR (95% CI) | OR (95% CI) | |
| Exposure | ||||
| <GJH41 | 5 | 145 | 1.00 | 1.00 |
| ≥GJH41 | 7 | 143 | 1.42 (0.44–4.58) | 1.37 (0.42–4.43)c |
| <GJH52 | 6 | 216 | 1.00 | |
| ≥GJH52 | 6 | 72 | 3.00 (0.94–9.60) | NCd |
| <GJH63 | 9 | 241 | 1.00 | |
| ≥GJH63 | 3 | 47 | 1.71 (0.45–6.55) | NCd |
1< GJH4 versus ≥ GJH4 = 3 versus 4 or more positive Beighton tests out of a maximum of 9 Beighton tests 2< GJH5 versus ≥ GJH5 = 4 versus 5 or more positive Beighton tests out of a maximum of 9 Beighton tests 3< GJH6 versus ≥ GJH6 = 5 versus 6 or more positive Beighton tests out of a maximum of 9 Beighton tests.
aOutcome (arthralgia) measured at follow-up at 14 years old, exposure (GJH) measured at baseline at eight or ten years old (cohort study). bUnivariate model. cMultivariable model adjusted to gender. dNo confounders identified for this association and no multivariable models conducted. NC = not conducted.