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. Author manuscript; available in PMC: 2015 Jan 24.
Published in final edited form as: Immunity. 2014 Jan 9;40(1):128–139. doi: 10.1016/j.immuni.2013.12.007

Figure 1. Pro-inflammatory phenotype of colonic CD4+T cells from Niacr1−/− mice.

Figure 1

(A) Foxp3 expression by CD4+ T cells from colonic lamina propria (LP) and spleens of WT and Niacr1−/− mice.

(B) Percent of Foxp3+ in CD4+ populations from colonic LP and spleens of WT and Niacr1−/− mice (n=3).

(C and E) IL-10 and IL-17 expression by (PMA+ionomycin)-stimulated colonic LP and splenic CD4+ T cells from WT and Niacr1−/− mice.

(D and F) Quantification of IL-10 and IL-17 producing CD4+ T cells shown in C and E respectively (n=3).

The numbers in A, C and E represent percentage of positive cells in indicated area. Error bars represent standard deviation (SD) of mean. *p<0.002. A representative of 3 independent experiments is shown.