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. 2015 Jan 24;10(1):e0115709. doi: 10.1371/journal.pone.0115709

Figure 4. PAS stained isografts (A) and allografts with vehicle treatment (B) or EA-230 50mg/kg (C) treatment six days after transplantation.

Figure 4

Isografts had no signs of acute rejection or acute tubular necrosis. Vehicle treated allografts showed severe ATN with 50% of the tubuli affected and Banff 1A acute rejection with interstial infiltrates, tubulitis and gomerulitis (B). EA-230 treated allografts (C) showed mild ATN with ∼10% of tubuli affected and borderline rejection (magnification 200 fold, D semiquantitative score for ATN).