Table 4. Selected KEGG gene pathways overrepresented in a cross sectional comparison of ABC versus AZT and TDF.
| Time | Pathway | KID | Adj p value | OR | Expected count | Observed count | |
|---|---|---|---|---|---|---|---|
| ABC-TDF | 6 m | Leukocyte transendothelial migration | 4670 | 0.03 | 1.6 | 22.3 | 32 |
| WNT signalling pathway | 4301 | 0.01 | 1.8 | 27.2 | 37 | ||
| ECM-receptor interaction | 4512 | 0.04 | 1.6 | 16.3 | 23 | ||
| ABC-AZT | 6m | Neuroactive ligand receptor interaction | 4080 | <0.0001 | 2.6 | 20.1 | 48 |
| ECM-receptor interaction | 4512 | 0.02 | 1.9 | 12.3 | 20 | ||
| Leukocyte transendothelial migration | 4670 | 0.04 | 1.7 | 12.1 | 19 |
KID = KEGG pathway ID; OR = odds ratio; Time = months on treatment; adj = adjusted