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Nonvascular malignancies have LMO2+ vasculature, except hepatocellular carcinoma and a subset of clear cell renal cell carcinomas. A, B, and C, Lung adenocarcinoma (A, ×400), glioblastoma (B, ×400), and mesothelioma (C, ×400) have LMO2+ vasculature. D and E, Clear cell renal cell carcinomas may have LMO2+ (D, ×400) or LMO2− (E, ×400) vasculature. F, Hepatocellular carcinoma has LMO2− vasculature (arrows, LMO2− vessels; ×400).
