Table 1.
Healthy controls (n = 188) |
MCI & AD subjects (n = 318) |
|
---|---|---|
Age (years) | 76.12±5.13 | 74.91±7.52 |
Percent female subjects | 46% | 46% |
Education (years) | 16.10±2.81* | 15.34±3.01* |
Percent carriers of APOE ε4 | 28%* | 64%* |
MMSE | 29.13±.97* | 25.16±2.49* |
ADAS-cog | 6.15±2.85* | 15.38±5.86* |
Data are given as mean±SD unless otherwise specified as a percent.
The MCI and AD subjects had a significantly lower level of education (p = .005), higher frequency of the APOE ε4 allele (p < .001) and significantly more impaired MMSE (p < .001) and ADAS-cog (p < .001) scores at baseline than the healthy controls