Table 2.
Diagnosis (n) | Genotypes | Allele frequencies | χ2-test | |||||
---|---|---|---|---|---|---|---|---|
C-629A | CC(%) | AC(%) | AA(%) | C | A | χ2 | df | p |
HC (188) | 50 (26.7) | 97 (51.9) | 40 (21.4) | 52.7 | 47.3 | 2.289 | 2 | .318* |
MCI, AD (318) | 76 (23.9) | 172 (54.1) | 70 (22.0) | 50.9 | 49.1 | |||
I405V | II(%) | IV(%) | VV(%) | I | V | χ2 | df | p |
HC (188) | 99 (52.7) | 73 (38.8) | 16 (8.5) | 72.1 | 27.9 | 0.043 | 2 | .979* |
MCI, AD (318) | 139 (43.7) | 147 (46.2) | 32 (10.1) | 66.8 | 33.2 |
Distribution of the CETP C-629A and I405V polymorphisms in healthy controls and subjects with MCI or AD.
Both polymorphisms were in Hardy-Weinberg equilibrium in the study population