Table 5.
Variable | df | F | Sig. |
---|---|---|---|
Male I405V | 2 | 2.309 | .100 |
Female I405V | 2 | 4.504 | .012* |
Male I405V*Age | 2 | 2.343 | .097 |
Female I405V*Age | 2 | 4.374 | .013* |
Age | 1 | 15.208 | 1.10E-4* |
Diagnosis | 1 | 125.971 | 3.45E-26* |
Sex | 1 | .166 | .684 |
APOE ε4 status | 1 | .251 | .617 |
Univariate general linear model factor by covariate analysis of variance was used for parahippocampal gyrus thickness, with I4045V genotype as a grouping factor and age, sex, diagnosis and APOE ε4 carrier status as covariates. There were no significant I405V genotype by age interactions with entorhinal cortex thickness or hippocampal volume. There were no significant C-629A genotype by age interactions in any of the three brain structures tested.
Statistically significant p-values (p < .05) are represented in bold