Table 3.

Odds Ratio of Low Lumbar and Total Bone Mass by Serum Bicarbonate Level

	Men	Women
Low Lumbar Bone Mass
Continuous*	0.95 (0.85,1.06)	0.93 (0.83,1.05)
< 24 mEq/L	1.00 (reference)	1.00 (reference)
24-25 mEq/L	1.29 (0.87,1.91)	0.96 (0.75,1.24)
25.1-26.9 mEq/L	1.21 (0.87,1.70)	0.94 (0.74,1.21)
≥ 27 mEq/L	0.90 (0.62,1.31)	0.79 (0.56,1.12)
P for trend	0.5	0.2
Low Total Bone Mass
Continuous*	0.96 (0.85,1.08)	0.91 (0.79,1.04)
< 24 mEq/L	1.00 (reference)	1.00 (reference)
24-25 mEq/L	0.91 (0.68,1.23)	1.05 (0.77,1.43)
25.1-26.9 mEq/L	1.03 (0.75,1.43)	0.92 (0.63,1.35)
≥ 27 mEq/L	0.85 (0.59,1.23)	0.68 (0.46,0.99)
P for trend	0.5	0.08

Note: Values are given as odds ratio (95% confidence interval). Bold values indicate p<0.05. Models adjusted for age, race/ethnicity, body mass index, poverty, education, activity level, smoking status, fasting length, diuretic and calcium carbonate use, diagnosis of diabetes mellitus, hypertension and cardiovascular disease, estimated glomerular filtration rate, albuminuria, serum albumin, calcium, phosphate and C-reactive protein.

^*Per 1-standard deviation higher serum bicarbonate (standard deviation = 2.2 mEq/L).