Table 1.
Classification of All Human Putative Protein-coding Genes into Categories based on Expression Patterns in Skin and Other Human Tissue Types.
| Category | Description | Number of Genes | Fraction (%) |
|---|---|---|---|
| Skin enriched | At least five-fold higher mRNA levels in skin as compared to all other tissues | 106 | 0.5 |
| Group enriched | At least five-fold higher mRNA levels in a group of 2–7 tissues, including skin | 149 | 0.7 |
| Skin enhanced | At least five-fold higher mRNA levels in skin as compared to average levels in all tissues | 162 | 0.8 |
| Expressed in all | Detected in all tissues (FPKM > 1) | 9,222 | 46 |
| Mixed | Detected in 2–27 tissues, but not elevated in skin | 3,558 | 18 |
| Not detected in skin | FPKM less than 1 in skin | 5,131 | 26 |
| Not detected in any tissue | FPKM less than 1 in all tissues | 1,722 | 9 |
| Total | Total number of genes analyzed with RNA-seq | 20,050 | 100 |
| Total elevated in skin | Total number of skin-enriched, group-enriched, and skin-enhanced genes expressed in skin | 417 | 2 |
FPKM, fragments per kilobase of exon model per million mapped reads.