Table 3.
Differential molecular function profile in cell lines Hca-F vs Hca-P.
| Transporter activity | |||
| Gja1 gb: BC006894 | 6.4 | Slc38a4 gb: AK003626 | 3.4 |
| gb: M63801 | 7.2 | gb: NM_027052 | 9 |
| Ramp3 | 3.6 | Rab3b | 5.6 |
| Scn8a | 4 | ||
| Tptih | 3.3 | ||
| Structural molecule activity | |||
| Eppk1 | 3.6 | Cldn9 | 7.4 |
| Col8a1 | 4.9 | Krt1-19 | 7.4 |
| Tuba4 | 3.3 | Krt2-7 | 5.2 |
| Krt2-8 gb: NM_031170 | 4.8 | Krt1-18 | 5.1 |
| gb: M21836 | 8.6 | ||
| Chaperone activity | |||
| Serpinh1 | 4 | Sncg | 5 |
| Motor activity | |||
| Myo1b gb: BI080370 | 3.2 | Myo1g | 3.3 |
| gb: AI255256 | 3.4 | ||
| Catalytic activity | |||
| Gcnt2 | 4.2 | Siat10 | 3.3 |
| Chst1 | 3.2 | Loxl2 | 3.7 |
| Ltb4dh | 5.2 | 2310047E01Rik | 3.1 |
| Hydrolase activity | |||
| Pla2g1b | 6.4 | Smpd2 | 4.3 |
| Abhd3 | 3.6 | Ptpn8 | 5.6 |
| Ptpre | 3 | Chi3l3 | 4.1 |
| Rrad | 3.4 | Rab3b | 5.6 |
| Chi3l4 | 3.4 | Ptprr | 4.1 |
| Pla2g7 | 4.4 | Fbp2 | 7.1 |
| Psmb8 | 3 | ||
| Kinase activity | |||
| Ccnd1 gb: M64403 | 3.2 | Krt2-8 gb: NM_031170 | 4.8 |
| gb: NM_007631 | 3.1 | gb: M21836 | 8.6 |
| A530090O15Rik | 3.4 | ||
| Protein-tyrosine kinase activity | |||
| Sgk2 | 3.1 | Egfr gb: AF275367 | 6.9 |
| Axl | 4 | gb: U03425 | 3.6 |
| Ripk3 | 6.4 | ||
| Transmembrane receptor protein kinase activity | |||
| Egfr gb: AF275367 | 6.9 | ||
| gb: U03425 | 3.6 | ||
| Protein serine/threonine kinase activity | |||
| Sgk2 | 3.1 | Mak | 3.9 |
| Axl | 4 | Egfr gb: AF275367 | 6.9 |
| Ripk3 | 6.4 | gb: U03425 | 3.6 |
| Transferase activity | |||
| A530090O15Rik | 3.4 | Axl | 4 |
| Ccnd1 gb: M64403 | 3.2 | Egfr gb: AF275367 | 6.9 |
| gb: NM_007631 | 3.1 | gb: U03425 | 3.6 |
| Chst1 | 3.2 | Gcnt2 | 4.2 |
| Krt2-8 gb: NM_031170 | 4.8 | Mak | 3.9 |
| gb: M21836 | 8.6 | Ripk3 | 6.4 |
| Sgk2 | 3.1 | Siat10 | 3.3 |
| Enzyme regulator activity | |||
| Ccnd1 gb: M64403 | 3.2 | Lxn | 3.1 |
| gb: NM_007631 | 3.1 | Timp1 | 3.2 |
| Sh3bp5 | 5.5 | Cd109 | 5.9 |
| 1600023A02Rik | 5.3 | Serpinh1 | 4 |
| Binding | |||
| Nucleic acid binding | |||
| Fosl1 gb: NM_010235 | 5 | Ankrd1 gb: NM_013468 | 5.3 |
| gb: U34245 | 4.3 | gb: AK009959 | 3.6 |
| Nr1d1 | 4.6 | ||
| Metal ion binding | |||
| Pla2g1b | 6.4 | Smpd2 | 4.3 |
| Ltb4dh | 5.2 | Scn8a | 4 |
| 2310047E01Rik | 3.1 | Pcdhb7 | 4.9 |
| 2810003C17Rik | 4.6 | Loxl2 | 3.7 |
| Zdhhc2 | 3.5 | ||
| Nucleotide binding | |||
| A530090O15Rik | 3.4 | Axl | 4 |
| Egfr gb: AF275367 | 6.9 | Krt2-8 gb: NM_031170 | 4.8 |
| gb: U03425 | 3.6 | gb: M21836 | 8.6 |
| Mak | 3.9 | Rab3b | 5.6 |
| Myo1b gb: BI080370 | 3.2 | Ripk3 | 6.4 |
| gb: AI255256 | 3.4 | Rrad | 3.4 |
| Scn8a | 4 | Sgk2 | 3.1 |
| Tuba4 | 3.3 | ||
| Receptor binding | |||
| Areg | 4.3 | Csf3 | 4.7 |
| Dok1 | 3.6 | Fgf15 | 5.4 |
| Il24 | 5.9 | Pla2g1b | 6.4 |
| Protein binding | |||
| Ankrd1 gb: NM_013468 | 5.3 | Ccnd1 gb: M64403 | 3.2 |
| gb: AK009959 | 3.6 | gb: NM_007631 | 3.1 |
| Cav | 5.8 | Cdc42ep5 | 4.4 |
| Col8a1 | 4.9 | Eng | 4.5 |
| D7Ertd458e | |||
| gb: BC013673 1423903_at 3.8 | Egfr gb: AF275367 | 6.9 | |
| gb: BB049138 1423904_a_at 4 | gb: U03425 | 3.6 | |
| gb: BB049138 1423905_at 3.9 | Fibp | 3.6 | |
| gb: NM_009310 4.2 | IL2rg gb: L20048 1416295_a_at 3.3 | ||
| gb: BC013673 1451160_s_at 4 | gb: L20048 1416296_at 4.3 | ||
| Itgb5 gb: NM_010580 | 3.5 | Igfbp6 | 3.3 |
| gb: NM_010580 | 3.3 | Lepr | 6.7 |
| Nol3 | 3.3 | Pcdhb7 | 4.9 |
| Procr | 4.6 | Ptpre | 3 |
| Rab3b | 5.6 | Rrad | 3.4 |
| Sh3bp5 | 5.5 | Tnfrsf22 | 3.5 |
| Fscn1 gb: NM_007984 1416514_a_at 5.4 | Myo1b gb: BI080370 | 3.2 | |
| gb: BE952057 | 4.2 | gb: AI255256 | 3.4 |
| gb: NM_007984 1448378_at 3.7 | Cnn2 | 5.2 | |
| Carbohydrate binding | |||
| Chi3l3 | 4.1 | Chi3l4 | 3.4 |
| Signal transducer activity | |||
| Dok1 | 3.6 | Ripk3 | 6.4 |
| Receptor activity | |||
| Axl | 4 | Itgb5 gb: NM_010580.1 | 3.5 |
| D7Ertd458e gb: BC013673 1423903_at 3.8 | gb: NM_010580.1 | 3.3 | |
| gb: BB049138 1423904_a_at 4 | Nr1d1 | 4.6 | |
| gb: BB049138 1423905_at 3.9 | Procr | 4.6 | |
| gb: NM_009310 4.2 | Ptpn8 | 5.6 | |
| gb: BC013673 1451160_s_at 4 | Ptprr | 4.1 | |
| Ramp3 | 3.6 | Tnfrsf19 | 3.4 |
| Tnfrsf22 | 3.5 | Lepr | 6.7 |
| IL2rg | gb: L20048.1 1416295_a_at 3.3 | Egfr gb: AF275367.1 | 6.9 |
| gb: L20048.1 1416296_at 4.3 | gb: U03425.1 | 3.6 | |
| F2r | 4.5 | ||