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Rates of improvement in anal burn and nausea.
| Symptom | Population | Racecadotril (%) | Loperamide (%) | P |
| Anal burn | ITT | 22/31 (71.0) | 23/31 (74.2) | 0.7353 |
| PP | 18/23 (78.3) | 19/25 (76.0) | 0.7428 | |
| Nausea | ITT | 23/31 (74.2) | 24/31 (77.4) | 0.659 |
| PP | 18/23 (78.3) | 20/25 (80.0) | 0.6475 |
