Histological examinations of specimens from the liver in each group. Livers from group MC (A), ME (B), FC (C), and FE (D) are shown. Sections of the liver from rats fed with control diet for 12 wk show normal histology with no evidence of pathologic change (A and C). Fat accumulation in female ethanol-fed rats was panlobular (D), but it was seen in pericentral areas in male ethanol-fed rats (B). (H&E stain, magnification: ×200).