Table 1.
Comparison between frequency of microsatellite LOH in different lesions of esophagus.
| MSM |
LOH frequency n (%) |
P | |||
| BCH | DYS | CIS | SCC | ||
| D3S1234 | 1/14 (7.1) | 3/12 (25) | 5/15 (33.30) | 9/23 (39.1) | 0.042 |
| D3S1300 | 0/11 (0) | 2/10 (20) | 4/10 (40) | 10/26 (38.5) | 0.024 |
| D3S966 | 0/13 (0) | 3/13 (23.1) | 8/16 (50) | 11/20 (55.0) | 0.001 |
| D5S82 | 0/12 (0) | 2/12 (16.7) | 6/15 (40) | 8/20 (40.0) | 0.010 |
| D5S346 | 2/12 (16.7) | 3/12 (25) | 4/10 (40) | 14/25 (56.0) | 0.011 |
| D6S497 | 0/10 (0) | 0/13 (0) | 0/12 (0) | 9/26 (34.6) | 0.001 |
| D9S1752 | 1/15 (6.7) | 2/12 (16.7) | 3/15 (20) | 5/25 (20.0) | 0.315 |
| D9S171 | 0/13 (0) | 5/16 (31.3) | 7/14 (50) | 14/23 (60.8) | 0.000 |
| D13S233 | 0/11 (0) | 3/13 (23.1) | 6/16 (37.5) | 10/21 (47.6) | 0.006 |
| D13S321 | 0/14 (0) | 3/12 (25) | 6/14 (42.9) | 11/25 (44.0) | 0.006 |
| D13S260 | 0/16 (0) | 4/12 (33.3) | 7/14 (50) | 16/26 (61.5) | 0.000 |
| D17S855 | 2/13 (15.4) | 4/14 (28.6) | 6/15 (40) | 14/26 (53.8) | 0.014 |
| TP53 | 3/15 (20) | 4/13 (30.8) | 7/16 (43.8) | 15/22 (68.2) | 0.002 |
| D17S786 | 0/14 (0) | 3/12 (25) | 6/15 (40) | 12/22 (54.5) | 0.001 |
| D18S858 | 0/13 (0) | 3/16 (18.8) | 4/12 (33.3) | 10/18 (55.6) | 0.000 |
MSM: microsatellite marker; LOH: loss of heterozygosity; BCH: basal cell hyperplasia DYS: dysplasia; CIS: carcinoma in situ; SCC: squamous cell carcinoma -: not done.