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. 2005 Apr 14;11(14):2095–2100. doi: 10.3748/wjg.v11.i14.2095

Table 8.

Pharmacodynamic comparation of emodin and baicalein[12-53].

Pharmacological function Emodin Baicalein
Antibiosis Escherichia coli, Dysentery Bacillus. Aureus staphylococcus G+,G- bacterium, fungi, spirilla
Anti-inflammation Inhibiting inflammatory cytokine release, restraining vascular permeability, inhibiting leukotrienes synthesis Anti-histamin release. anti-arachidonic acid metabolism, restraining vascular permeability, anti-allergy
Immunoregulation Enhance immunity (-)
Inhibiting pancreatin activity Strongly suppressive effect on multiple pancreatins Only on trypsogen
Protecting liver Anti-hepatofibrosis, antagonzism of liver damage by CCL4 Anti-hepatofibrosis,
Protecting kidney Inhibiting kidney compensative hypertrophy. Restraining proliferation of kidney fibroblast, preventing and curing earlier injury of kidney on rats with diabetes (-)
Protecting pancreas (+) (-)
Cholagog (+) (-)
Diuresis (+) (+)
Antioxidation (+) (+)
Scavenging free-radicals (+) (+)
Anti-thrombosis (+) (+)
Circulatory system Dilative effect on multiple blood vessel, depressing proliferation of vascular smooth muscle cell Double effects of vasodilatation and vasoconstriction
Gastrointestinal tract Double regulation of isolated intestine, anti-gastric ulcer,reducing gastric acid and pepsin, purgate Curative effect on acute and chronic gastroenteritis
Anti-endotoxemia (+) (+)
Fever relieving (–) (+)

“+”for positive pharmacological action; “–”for negative pharmacological action.