Table 2.
Correlation between the expression of E-cadherin in primary tumors and clinicopathologic characteristics.
| Variable | Patients (n) |
Expression of E-cadherin |
||
| Negative (%) | Positive (%) | P | ||
| Gender | ||||
| Male | 17 | 7 (41.2) | 10 (58.8) | |
| Female | 13 | 7 (53.8) | 6 (46.2) | P = 0.713 |
| Age | ||||
| <50 yr | 10 | 3 (30) | 7 (70) | |
| ≥R50 yr | 20 | 11 (55) | 9 (45) | P = 0.260 |
| Superficial diameter | ||||
| <5 cm | 17 | 7 (41.2) | 10 (58.8) | |
| ≥R5 cm | 13 | 7 (53.8) | 6 (46.2) | P = 0.713 |
| Tumor location | ||||
| Upper/middle third | 17 | 8 (47.1) | 9 (52.9) | |
| Lower third | 13 | 6 (46.2) | 7 (53.8) | P = 1.000 |
| Histologic type | ||||
| Intestinal | 11 | 2 (18.2) | 9 (81.8) | |
| Diffuse | 19 | 12 (63.2) | 7 (36.8) | P = 0.026 |
| Depth of invasion | ||||
| T1/T2 | 21 | 8 (38.1) | 13 (61.9) | |
| T3/T4 | 9 | 6 (66.7) | 3 (33.3) | P = 0.236 |
| Histologic differentiation | ||||
| Well/moderate | 13 | 2 (15.4) | 11 (84.6) | |
| Poor | 17 | 12 (70.6) | 5 (29.4) | P = 0.004 |
| Lymph node metastasis | ||||
| Positive | 18 | 12 (66.7) | 6 (33.3) | |
| Negative | 12 | 2 (16.7) | 10 (83.3) | P = 0.011 |
| Lymphatic invasion | ||||
| Positive | 18 | 13 (72.2) | 5 (27.8) | |
| Negative | 12 | 1 (8.3) | 11 (91.7) | P = 0.001 |