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. 2005 May 14;11(18):2726–2732. doi: 10.3748/wjg.v11.i18.2726

Table 4.

Characteristics of triple therapies consisting of a PPI, metronidazole and clarithromycin or amoxicillin.

Refs Combination regimens Dose Treatment duration Eradication rate (ITT)
P
PUD
NUD
N/T.N (%) N/T.N (%)
23 Pan/Met/Cla 40 mg q.d./400 mg b.i.d./250 mg b.i.d. 7 d 54/65 (83.1) 21/24 (87.5) 0.613
23 Pan/Met/Cla 40 mg b.i.d./400 mg b.i.d./250 mg b.i.d. 7 d 54/64 (84.4) 18/22 (81.8) 0.781
24 Ome/Met/Cla 40 mg q.d./500 mg b.i.d./250 mg b.i.d. 7 d 15/19 (78.95) 5/6 (83.3) 0.819
25 Pan/Met/Amo 40 mg b.i.d./500 mg b.i.d./1 g b.i.d. 7 d 14/19 (73.7) 7/11 (63.6) 0.569
26 Ome/Met/Amo 40 mg q.d./400 mg t.i.d.1/750 mg b.i.d. 14 d 22/27 (81.5) 22/37 (59.5) 0.063

Ome, omeprazole; Pan, pantoprazole; Cla, clarithromycin; Amo, amoxicillin; Met, metronidazole; daily; q.d., daily; b.i.d., twice daily. 1Metronidazole was used for 5 d only. PUD, peptic ulcer disease; NUD, non-ulcer dyspepsia.