Table 4.
Refs | Combination regimens | Dose | Treatment duration |
Eradication rate (ITT) |
P | |
PUD |
NUD |
|||||
N/T.N (%) | N/T.N (%) | |||||
23 | Pan/Met/Cla | 40 mg q.d./400 mg b.i.d./250 mg b.i.d. | 7 d | 54/65 (83.1) | 21/24 (87.5) | 0.613 |
23 | Pan/Met/Cla | 40 mg b.i.d./400 mg b.i.d./250 mg b.i.d. | 7 d | 54/64 (84.4) | 18/22 (81.8) | 0.781 |
24 | Ome/Met/Cla | 40 mg q.d./500 mg b.i.d./250 mg b.i.d. | 7 d | 15/19 (78.95) | 5/6 (83.3) | 0.819 |
25 | Pan/Met/Amo | 40 mg b.i.d./500 mg b.i.d./1 g b.i.d. | 7 d | 14/19 (73.7) | 7/11 (63.6) | 0.569 |
26 | Ome/Met/Amo | 40 mg q.d./400 mg t.i.d.1/750 mg b.i.d. | 14 d | 22/27 (81.5) | 22/37 (59.5) | 0.063 |
Ome, omeprazole; Pan, pantoprazole; Cla, clarithromycin; Amo, amoxicillin; Met, metronidazole; daily; q.d., daily; b.i.d., twice daily. 1Metronidazole was used for 5 d only. PUD, peptic ulcer disease; NUD, non-ulcer dyspepsia.