Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Dec 12;8(Suppl 5):S4. doi: 10.1186/1752-0509-8-S5-S4

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2014 Sriyudthsak et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Qualitative predictions of consequences of gene knockdown. The simplified aspartate-family biosynthesis pathway enlarged from Figure 4. Metabolites (AdoMet, S-adenosyl-methionine; Ala, alanine; Arg, arginine; Asn, asparagine; Asp, aspartate; AspSA, aspartate-semialdehyde; Cit, citrate; CisAc, cis-aconitate; Cys, cysteine; CysTA, cystathionine; DHDP, dihydrodipicolinate; Fum, fumalate; Gln, glutamine; Glu, glutamate; Gly, glycine; G6P, glucose-6-phosphate; Hcys, homocysteine; HSer, homoserine; His, histidine; Ile, iso-leucine; IsoCit, iso-citrate; α-KG, α-ketoglutarate; Leu, leucine; Lys, lysine; Mal, malate; Met, methionine; OAc, oxaloacetate; OPH, O-phosphohomoserine; Orn, ornitine; Phe, phenylalanine; Pro, proline; Pyr, pyruvate; Ser, serine; Suc, succinate; SucCoA, succinyl CoA; Thr, threonine; Trp, tryptophan; Tyr, tyrosine; Val, valine) are represented in black letters whereas the knocked-down gene (mto2, MTO2 encoding threonine synthase) is represented in green letters. Two squares boxes indicate the comparisons between experimental results (the former) and in silico prediction (the latter).