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. 2015 Jan 26;5:8032. doi: 10.1038/srep08032

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(a)–(c), (e), (f) Representative experiments on hTRPM2, nvTRPM2, empty vector control, nvTRPM2-hNUD and nvTRPM2-(Δ15) as indicated, showing the F340/F380 ratio over time. Extracellular H₂O₂ (10 mM) was added at time points marked with arrows. Maximal increases in F340/F380 are summarized in d. The inhibiting effect of extracellular Ca²⁺ removal is shown in panel f. ***Indicates a significant difference (P = 0.001) evaluated with a one-way ANOVA and the Bonferroni correction. n = 12–19. Error bars are s.e.