Hepatic metastases of colon cancer in the orthotopic transplant nude mouse model. A-D: HE staining of hepatic metastases tissues from mice in the CON, WCA, 5-FU and WCA + 5-FU groups (magnification × 200); E-H: Gross anatomy of mice in the CON, WCA, 5-FU and WCA + 5-FU groups. The black arrow indicates orthotopic tumor, the long white arrow indicates the hepatic metastatic tumor, and the short white arrow indicates the metastasis of colon cancer to the intestinal wall. WCA: Weichang’an; 5-FU: 5-fluorouracil; CON: Control.