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. 2015 Jan 28;21(4):1125–1139. doi: 10.3748/wjg.v21.i4.1125

Figure 4.

Figure 4

Immunohistochemistry detection of β-catenin and matrix metalloproteinase-7 in orthotopic tumors and hepatic metastatic tumors. A, B: Integrated optical density (OD) of β-catenin and matrix metalloproteinase (MMP)-7 protein expressed in orthotopic tumors (A) or hepatic metastatic tumors (B) from mice in the CON, WCA, 5-FU and WCA + 5-FU groups. Data are presented as mean ± SD and aP < 0.05 vs corresponding CON group; C: IHC staining for β-catenin in orthotopic tumors (magnification × 200); D: IHC staining for MMP-7 in orthotopic tumors (magnification × 200); E: IHC staining for β-catenin in hepatic metastatic tumors (magnification × 200); F: IHC staining for MMP-7 in hepatic metastatic tumors (magnification × 200). WCA: Weichang’an; 5-FU: 5-fluorouracil; CON: Control.