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. Author manuscript; available in PMC: 2015 Jan 26.
Published in final edited form as: Curr Metabolomics. 2014 Apr;2(1):53–69. doi: 10.2174/2213235X02666140301002510

Figure 5.

Figure 5

Histopathologic stage pT3a prostate cancer, Gleason score 5, in a 58-year old man. (A) Fast spin-echo T2-weighted (5000/102) transverse MR image through the middle gland was obtained with an endorectal coil. A tumor focus (arrows) is seen as an area of decreased signal intensity in the peripheral zone of the right gland. (b) The same section as in (A) shows areas of definite cancer, as demonstrated with 3D MRSI findings overlaid and circled. Note the concordance between (A) and (B). (C) MR spectrum obtained from area of imaging abnormality in the right peripheral zone demonstrates elevated choline and reduced citrate, a pattern consistent with definite cancer. (D) MR spectrum obtained from a normal left peripheral zone demonstrates a normal spectral pattern with citrate dominant and no abnormal elevation in choline. Reproduced with permission from Scheidler et al. Radiology (1999), 213 (2), pp. 473–480 RSNA.