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. Author manuscript; available in PMC: 2015 Jan 26.
Published in final edited form as: Cell Rep. 2014 Jul 24;8(3):831–842. doi: 10.1016/j.celrep.2014.06.047

Figure 7. Zinc Binding to Tau and Its Effect on Tau Phosphorylation Are Two Independent Events.

Figure 7

(A) Tau*C2A undergoes similar phosphorylation as Tau*. Shown are phosphorylation levels of Tau*, Tau*S2A, and Tau*C2A proteins as detected by western blots.

(B) Tau*C2H and Tau*C291H also undergo similar phosphorylation as Tau*. Shown are phosphorylation levels of Tau*, Tau*C2A, and Tau*C291H proteins.

(C) Phosphorylation of Tau*C2A is similarly affected by zinc. Elav-Gal4 was used to express the proteins in CNS. Tau5 was used to indicate the total Tau level, and actin was used as an additional loading control.