Table I.
Association between the clinicopathological characteristics of the 112 colorectal cancer patients and GAL expression.
| GAL expression | |||
|---|---|---|---|
|
|
|||
| Variables | High (n=14) | Low (n=98) | P-value |
| Age (years) | |||
| ≥65 | 8 (57.1) | 38 (38.8) | |
| <65 | 6 (42.9) | 60 (61.2) | 0.20 |
| Gender | |||
| Male | 9 (64.3) | 49 (50.0) | |
| Female | 5 (35.7) | 49 (50.0) | 0.31 |
| Location | |||
| Colon | 7 (50.0) | 65 (63.3) | |
| Rectum | 7 (50.0) | 33 (33.7) | 0.24 |
| pT stage | |||
| T2 | 0 (0.0) | 8 (8.2) | |
| T3 | 12 (85.7) | 81 (82.6) | |
| T4 | 2 (14.3) | 9 (9.2) | 0.30 |
| Stage | |||
| II | 11 (78.6) | 41 (41.8) | |
| III | 3 (21.4) | 57 (58.2) | 0.009a |
| Histology | |||
| Diff | 11 (78.6) | 85 (86.7) | |
| Undiff | 3 (21.4) | 13 (13.3) | 0.44 |
| Lymphatic invasion | |||
| Negative | 10 (71.4) | 59 (60.2) | |
| Positive | 4 (28.6) | 39 (39.8) | 0.41 |
| Venous invasion | |||
| Negative | 10 (71.4) | 52 (53.1) | |
| Positive | 4 (28.6) | 46 (46.9) | 0.19 |
| Histological surgical margin | |||
| Negative | 14 (100.0) | 94 (95.9) | |
| Positive | 0 (0.0) | 4 (4.1) | 0.30 |
| Adjuvant chemotherapy | |||
| Done | 9 (64.3) | 70 (71.4) | |
| Not done | 5 (35.7) | 28 (28.6) | 0.59 |
| Tumor recurrence | |||
| Negative | 4 (28.6) | 52 (53.1) | |
| Positive | 10 (71.4) | 46 (46.9) | 0.08 |
a
Statistical significance (P<0.05).
Diff, differentiated tumor; Undiff, undifferentiated tumor; GAL, galanin.