Figure 3.

Effect of silencing of ETS-1 on expression of EMT-associated genes. (A) qRT-PCR analysis of ETS-1, N-cadherin, E-cadherin and VEGF mRNA expression in the transfected Panc-1 cells. GAPDH was included as a normalization control. (B) Western blot analysis of protein expression of corresponding molecules in the Panc-1 cells after ETS-1 silencing. ETS-1, v-ets erythroblastosis virus E26 oncogene homolog 1; EMT, epithelial-mesenchymal transition; VEGF, vascular endothelial growth factor; GAPDH, glyceraldehyde-3-phosphate dehydrogenase.