FIGURE 3.

Transcriptional and post-translational regulation of GI. The expression of GI is regulated by LIGHT-REGULATED WD1/2 (LWD1/2), TIME FOR COFFEE (TIC), and CIRCADIAN CLOCK ASSOCIATED 1 (CCA1) in the day and EVENING COMPLEX (EC) night time repressor during night, such that the transcript peaks at around ZT 10 in LD and ZT 8 in SD. In the dark phase, 26S Proteasome, CONSTITUTIVE PHOTOMORPHOGENESIS 1 (COP1), and EARLY FLOWERING 3 (ELF3) regulate the abundance of the protein. SUMOylation of GI stabilizes the protein.