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. 2015 Jan 26;5:3. doi: 10.3389/fonc.2015.00003

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Copyright © 2015 Johansson, Tabor, Wikell, Jalkanen and Fuxe.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The EMT-induced monocyte/macrophage cluster is linked to EMT in human breast cancer. (A,B) Bar graphs showing that the average expression level of the EMT-induced monocyte/macrophage cluster was increased in human breast cancer cell lines displaying EMT vs. non-EMT properties, and in basal B cells compared to luminal and basal A cells. (C,D) Bar graphs showing that the average expression level of the EMT-induced monocyte/macrophage cluster was increased in human breast cancer samples negative for estrogen and progesterone receptors (ER−/PR−) compared to ER+/PR+ tumors, and in tumors displaying EMT vs. non-EMT properties.