Figure 2.

Relationship between the status of thiol repair systems and the loss of vision acuity in human lenses with cortical or nuclear opacity. Cortical (n = 17) and nuclear (n = 15) cataractous lenses were selected and divided into two groups based on visual acuity: group A: optical chart reading (R), counting fingers (CF); group B: hand motion (HM), light perception (LP). Samples included cortical A (n = 13), cortical B (n = 4), nuclear A (n = 11), nuclear B (n = 4), and control (n = 8) cataract samples. Each sample homogenate was assayed for GR, TR, TTase, and TRx activities and GSH level. Data are means ± SD. *P < 0.05 by comparison with control. (A) GSH level; (B) GR activity; (C) TTase activity; (D) TR activity; (E) Trx activity.