Table 3.
Acid-base parameters and electrolytesa.
| Hour 0 | Hour 8 | Hour 16 | Hour 24 | Hour 36 | Hour 48 | Hour 60 | Hour 72 | Hour 96 | |
|---|---|---|---|---|---|---|---|---|---|
| pH | 7.32 ± 0.12 | 7.37 ± 0.08 | 7.37 ± 0.10 | 7.37 ± 0.08 | 7.39 ± 0.09 | 7.37 ± 0.08 | 7.38 ± 0.07 | 7.38 ± 0.07 | 7.37 ± 0.11 |
| (n = 18) | (n = 18) | (n = 18) | (n = 18) | (n = 19) | (n = 17) | (n = 18) | (n = 18) | (n = 17) | |
|
| |||||||||
| pCO2 (mmHg) | 42.0 ± 14.6 | 37.3 ± 12.6 | 38.1 ± 9.7 | 39.9 ± 10.3 | 40.1 ± 11.6 | 39.4 ± 11.6 | 40.6 ± 10.3 | 42.2 ± 10.2 | 43.8 ± 16.1 |
| (n = 18) | (n = 18) | (n = 18) | (n = 18) | (n = 19) | (n = 17) | (n = 18) | (n = 18) | (n = 17) | |
|
| |||||||||
| HCO3 (mmol/L)b | 19.8 ± 5.1 | 20.1 ± 5.1 | 19.7 ± 4.2 | 22.3 ± 3.9 | 22.8 ± 3.7 | 23.1 ± 3.2 | 22.8 ± 3.5 | 23.3 ± 2.4 | 23.2 ± 3.8 |
| (n = 19) | (n = 18) | (n = 18) | (n = 18) | (n = 19) | (n = 17) | (n = 18) | (n = 16) | (n = 16) | |
|
| |||||||||
| Base excess (mmol/L) | −5.2 ± 6.5 | −4.2 ± 5.4 | −3.9 ± 5.4 | −3.3 ± 3.6 | −2.2 ± 3.0 | −2.3 ± 2.7 | −1.8 ± 3.3 | −1.2 ± 2.6 | −1.4 ± 3.3 |
| (n = 18) | (n = 18) | (n = 18) | (n = 18) | (n = 19) | (n = 17) | (n = 18) | (n = 18) | (n = 17) | |
|
| |||||||||
| Sodium (mmol/L) | 132.7 ± 6.5 | 132.8 ± 5.1 | 132.5 ± 5.6 | 132.5 ± 5.9 | 132.1 ± 3.9 | 132.1 ± 3.9 | 132.1 ± 4.2 | 132.4 ± 4.1 | 131.1 ± 3.8 |
| (n = 19) | (n = 18) | (n = 18) | (n = 18) | (n = 19) | (n = 17) | (n = 18) | (n = 16) | (n = 16) | |
|
| |||||||||
| Potassium (mmol/L) | 4.9 ± 1.0 | 4.6 ± 0.8 | 4.6 ± 0.7 | 4.6 ± 0.7 | 4.5 ± 0.6 | 4.5 ± 0.8 | 4.4 ± 0.4 | 4.3 ± 0.5 | 4.5 ± 0.5 |
| (n = 19) | (n = 19) | (n = 18) | (n = 19) | (n = 19) | (n = 19) | (n = 18) | (n = 17) | (n = 16) | |
|
| |||||||||
| Chloride (mmol/L) | 96.4 ± 6.2 | 97.2 ± 5.7 | 97.4 ± 4.5 | 97.3 ± 5.4 | 98.5 ± 4.6 | 99.2 ± 3.5 | 98.2 ± 4.1 | 99.3 ± 3.7 | 98.8 ± 4.0 |
| (n = 19) | (n = 18) | (n = 18) | (n = 18) | (n = 19) | (n = 17) | (n = 18) | (n = 16) | (n = 16) | |
|
| |||||||||
| Ionized calcium (mg/dL) | 1.03 ± 0.1 | 1.08 ± 0.3 | 1.05 ± 0.1 | 1.04 ± 0.1 | 1.03 ± 0.1 | 1.08 ± 0.1 | 1.09 ± 0.1 | 1.11 ± 0.1 | 1.11 ± 0.1 |
| (n = 19) | (n = 16) | (n = 17) | (n = 19) | (n = 18) | (n = 16) | (n = 18) | (n = 16) | (n = 15) | |
|
| |||||||||
| BUN (mg/dL) | 68.4 ± 35.8 | 60.2 ± 33.2 | 51.8 ± 27.1 | 45.4 ± 22.5 | 40.1 ± 20.2 | 37.5 ± 18.9 | 34.1 ± 16.4 | 30.5 ± 15.2 | 29.4 ± 14.6 |
| (n = 19) | (n = 18) | (n = 18) | (n = 18) | (n = 19) | (n = 17) | (n = 18) | (n = 16) | (n = 16) | |
|
| |||||||||
| Creatinine (mg/dL) | 3.9 ± 1.2 | 3.5 ± 1.2 | 3.1 ± 1.1 | 2.8 ± 1.0 | 2.4 ± 1.0 | 2.3 ± 0.8 | 2.0 ± 0.7 | 2.0 ± 0.7 | 1.7 ± 0.7 |
| (n = 19) | (n = 18) | (n = 18) | (n = 18) | (n = 19) | (n = 17) | (n = 18) | (n = 16) | (n = 16) | |
aValues presented as mean ± standard deviation.
bDrawn from venous chemistry panel.
pCO2: partial arterial pressure of carbon dioxide, HCO3: bicarbonate, and BUN: blood urea nitrogen.