Table 2. Baseline Characteristics of TINSAL-CVD male participants with cognitive function tests.
Continuous data are presented as the mean and standard deviation or median and interquartile range and categorical data as counts and percentages.
| Variable | Result | Conventional Unit |
|---|---|---|
| N | 226 | |
| Male sex (%) | 226 (100.0) | |
| Race/Ethnicity | ||
| - Caucasian | 212 (93.8) | |
| - African American | 4 (1.8) | |
| - Asian | 5 (2.2) | |
| - Multi-Racial | 5 (2.2) | |
| Age (years) | 61 ± 6.9 | |
| Weight (kg) | 96.9 ± 12.0 | |
| BMI (kg/m2) | 31.4 ± 3.0 | |
| Waist Circumference (cm) | 107.7 ± 8.6 | |
| Blood Pressure | ||
| - Systolic (mmHg) | 128 ± 12.7 | |
| - Diastolic (mmHg) | 75 ± 8.0 | |
| - Mean Arterial Pressure (mmHg)a | 93 ± 8.5 | |
| - Heart Rate (bpm) | 61 ± 9.6 | |
| Glycemiab | ||
| - Normal Glucose Tolerance | 139 (61.5) | |
| - Impaired Fasting Glucose | 47 (20.8) | |
| - Type 2 Diabetes | 40 (17.7) | |
| Cardiac Risk Factor History | ||
| - Hypertension | 153 (67.7) | |
| - High LDL Cholesterol | 200 (88.5) | |
| - Low HDL Cholesterol | 173 (76.6) | |
| - High Triglycerides | 140 (62.0) | |
| - Smoking Statusc | ||
| ○ Current Smoker | 37 (16.4) | |
| ○ Former Smoker | 64 (28.3) | |
| ○ Non Smoker | 125 (55.3) | |
| Past Medical/Surgical History | ||
| - Coronary Heart Disease | ||
| ○ Previous Myocardial Infarction | 141 (62.4) | |
| ○ Stable Angina | 89 (39.4) | |
| ○ Angioplasty/Stent | 152 (67.3) | |
| ○ Previous Coronary Artery Bypass Surgery | 54 (23.9) | |
| ○ Abnormal Exercise Tolerance Test | 88 (38.9) | |
| ○ Significant Non-Calcified Plaque | 5 (2.21) | |
| - Vascular Disease | ||
| ○ Stroke | 4 (1.8) | |
| ○ Transient Ischemic Attack | 3 (1.3) | |
| ○ Carotid Vascular Disease | 6 (2.7) | |
| ○ Carotid Endartectomy | 3 (1.3) | |
| ○ Peripheral Vascular Disease | 9 (4.0) | |
| ○ Peripheral Artery Bypass Surgery | 3 (1.3) | |
| ○ Peripheral Artery Angioplasty | 3 (1.3) | |
| - Psychologicald | ||
| ○ Depression | 37 (16.4) | |
| ○ Counseling for Psychological Problems | 25 (11.1) | |
| ○ Medicines for Psychological Problems | 22 (9.8) | |
| ○ Anxiety | 9 (4.0) | |
| Years of School Completed | ||
| - 11–14 | 71 (31.7) | |
| - 15–18 | 116 (51.8) | |
| - 19–22 | 31 (13.8) | |
| - 23–26 | 6 (2.7) | |
| - Unknown | 2 (0.9) | |
| Laboratory Results | ||
| - Glucose (mmol/L) | 5.49 | 99.0± 18.1 (mg/dL) |
| - Hemoglobin A1c (mmol/mol) | 41.0 | 5.9 ± 0.49 (%) |
| - Lipid Profile (mmol/L) | ||
| ○ Total Cholesterol | 3.90 | 150.8 ± 31.1 (mg/dl) |
| ○ HDL Cholesterol | 1.14 | 44.1 ± 11.3 (mg/dl) |
| ○ LDL Cholesterol | 2.03 | 78.4 ± 25.7 (mg/dl) |
| ○ Triglycerides | 1.63 | 144.1 ± 90.3 (mg/dl) |
| ○ Non HDL Cholesterole | 5.9 | 106.7 ± 29.7 (mg/dl) |
| - Serum Creatinine (mg/dL) | 84.9 | 0.96 ± 0.17 (mg/dl) |
| - Estimated Creatinine Clearance (mL/s)f | 1.90 | 114.0 ± 27.4 (ml/min) |
| - Microalbumin Creatinine Ratio | ||
| ○ Normal (<3.39 mg/mmol creatinine) g | 214 (95.5) | |
| ○ Microalbuminia(3.39–33.8mg/mmol creatinine)h | 10 (4.5) | |
| SF-36 Health Survey Score | ||
| - Physical Health (0–100) | 81 (73–88) | |
| - Mental Health (0–100) | 86 (78–90) | |
| - Total SF-36 (0–100) | 86 (79–91) | |
| Cognitive Function | ||
| - Mini-Mental State Examination | 29 (28–30) | |
| - Digit Symbol Substitution Test | 61 (53–71) | |
| - Rey Auditory Verbal Learning Test | ||
| ○ Sum of the First 4 Trials on List A | 30 (26–35) | |
| ○ Short Delay for List A | 6 (5–8) | |
| ○ Delayed Recall of List A | 6 (5–8) | |
| ○ Delayed Recognition of List A | 23 (22–24) | |
| - Trail Making Tests | ||
| ○ Trail A (in seconds) | 29 (24–36) | |
| ○ Trail B (in seconds) | 72 (57–100) | |
| - Categorical Verbal Fluency | ||
| ○ Score 1 – Sum of Animals | 20 (17–24) | |
| ○ Score 2 – Sum of Supermarket Items | 25 (21–29) | |
| ○ Score 3 – Sum of Score 1 and Score 2 | 45 (39–52) | |
| ○ Score 4 – Average of Score 1 and Score 2 | 23 (20–26) | |
Data are means ± SD, n (%) or median (25th–75th percentile).
Mean arterial pressure: [(2*Diastolic) + Systolic]/3
Normal glucose tolerance determined by fasting glucose <5.55 mmol/L (100 mg/dl) and HbA1c <6.5% (47.5 mmol/mol); Impaired fasting glucose determined by fasting glucose between 5.55 mmol/L and 6.94 mmol/L (100 to 126 mg/dl) and HbA1c <6.5% (47.5 mmol/mol); and type 2 diabetes determined by medical history of diagnosis or fasting glucose ≥6.94 mmol/L (126 mg/dl) or HbA1c ≥6.5% (47.5 mmol/mol)
Smoking: if stopped 15 years or more then not a smoker
Self-reported: past medical history self-report of psychological conditions
Non-HDL Cholesterol = Total Cholesterol − HDL Cholesterol
Cockroft-Gault creatinine clearance = ((140-age) × weight (kg))/plasma creatinine × 72 for men (normal 95–145 ml/min)
less than 30 μg/mg creatinine
30–299 μg/mg creatinine