Figure 2.

Concentration-dependent inhibition curves of compstatin peptides in C3b and C5b-9 ELISAs and hemolytic assays. Data show C3b, C5b-9, and hemolysis inhibition (from left to right) for set 1 (A–C), set 2 (D–F), set 3 (G–I), set 4 (J–L), set 5 (M–O), and control (P–R) peptides. Data points indicate mean percent inhibition ± SEM (standard error of the mean). The intersection of dashed lines shows the IC₅₀ value for meW4A9 in all plots. Curves to the right and left of the intersection point represent peptides with higher IC₅₀ values and lower IC₅₀ values compared to meW4A9, respectively.