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Performance of the ANN model 1 (spectra only) and model 2 (spectra plus anatomical segmentation) in validation data set (796 voxels): area under ROC curve (AUC) and sensitivity and specificity at confidence level of 0.5.
| AUC | Sensitivity (%) | Specificity (%) | ||
|---|---|---|---|---|
| Estimate | 95% CI | |||
| Model 1 | 0.949 | 0.909 – 0.990 | 50.0 (8/16) | 98.7 (770/780) |
| Model 2 | 0.968 | 0.937 – 0.999 | 62.5 (10/16) | 99.0 (772/780) |
Note: AUC for model 2 is significantly higher than AUC of model 1 (p = 0.03) (15).
