. Author manuscript; available in PMC: 2016 Jan 31.

Published in final edited form as: Transl Res. 2014 Sep 6;165(2):358–359. doi: 10.1016/j.trsl.2014.08.007

Table 1.

SNPs associated with diameters and stiffness with a p value <0.05^*

Gene	SNP	BP	Minor/Major allele (MAF)	Trait	Beta (95% CI)	P
SIRT1	rs7895833	69293063	G/A (0.24)	Stiffness, log-transformed	−0.06 (−0.12, −0.01)	0.027
SIRT5	rs10498683	13668813	T/C (0.14)	Stiffness, log-transformed	0.07 (0.00, 0.13)	0.045
UCP1	rs7693034	141698129	G/C (0.48)	Diastolic diameter	0.11 (0.03, 0.19)	0.007
				Systolic diameter	0.11 (0.03, 0.19)	0.007
	rs12502572	141704584	A/G (0.49)	Diastolic diameter	0.10 (0.02, 0.18)	0.011
				Systolic diameter	0.10 (0.03, 0.18)	0.010
	rs1430583	141706434	T/C (0.23)	Diastolic diameter	0.12 (0.03, 0.21)	0.010
				Systolic diameter	0.11 (0.02, 0.20)	0.017
	rs6818140	141707405	G/A (0.23)	Diastolic diameter	0.12 (0.03, 0.20)	0.011
				Systolic diameter	0.11 (0.02, 0.20)	0.018
UCP3	rs1800849	73397813	A/G (0.15)	Diastolic diameter	0.11 (0.00, 0.22)	0.046
UCP5	rs5977238	129308417	A/G (0.06)	Diastolic diameter	−0.21 (−0.38, −0.05)	0.012
				Systolic diameter	−0.23 (−0.40, −0.06)	0.007

adjusted for age, sex, current smoking, obesity, diabetes, and the top three PCAs.