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. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: Ophthalmology. 2014 Oct 3;122(2):345–355. doi: 10.1016/j.ophtha.2014.08.017

Figure 8. Disease progression in an ABCA4-positive patient.

Figure 8

AF images from three visits (A-C) are shown for the brother of P15 at the indicated ages, illustrating that patients with a BEM phenotype can develop extramacular disease and flecks. This patient was not included in the study (due to presence of peripheral flecks) but also carries the complex allele L541P/A1038V.