Table 4.
Multivariate linear regression* analysis for factors associated with visual acuity score (letters) at Year 1 among eyes with hemorrhage > 50% at baseline (N=78 with Year 1 visual acuity)
Factor | Subjects | Mean Visual Acuity Score (Standard Error) | P value |
---|---|---|---|
Baseline visual acuity (per letter decrease) | 78 | −0.76 (0.12) | <0.0001 |
Baseline area of choroidal neovascularization, disc areas | |||
<=1 | 38 | 69.8 (2.33) | 0.03 |
>1 | 12 | 61.7 (4.19) | |
Unknown | 28 | 60.7 (2.78) | |
Taking AREDS supplements | |||
No | 24 | 60.1 (29.3) | 0.04 |
Yes | 54 | 67.5 (1.95) | |
Treatment Group | |||
Ranibizumab monthly | 20 | 63.8 (3.22) | 0.87 |
Bevacizumab monthly | 16 | 67.8 (3.59) | |
Ranibizumab as needed | 21 | 65.0 (3.14) | |
Bevacizumab as needed | 21 | 65.3 (3.11) |
The full, initial model included baseline visual acuity, baseline area of choroidal neovascularization, taking AREDS supplements, occult neovascularization, smoking status, total retinal thickness, treatment group.