Changes in the subjective skin condition with time following ingestion of hyaluronans and placebo. The subjective skin conditions, i.e., luster, suppleness, and wrinkles, were evaluated using a questionnaire prior to ingestion, 3 and 6 weeks of ingestion, and 2 weeks after ingestion ended. Differences in each questionnaire result relative to the baseline condition (⊿): (A) luster, (B) suppleness, and (C) wrinkles. indicates the placebo group; indicates the HA 800 k group; indicates the HA 300 k group. Dunnett’s test was used to compare the three groups. Data are present as means ± SE. †p<0.10 and *p<0.05.