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Enzyme kinetic parameters for RA formation from retinal by ALDH1A enzymes
| Enzyme | at-Retinal | 13-cis-Retinal | |||||
| kcat (min−1) | Km (nM) | Clint (ml/min/pmol) | kcat (min−1) | Km (nM) | Ki (nM) | Clint (μl/min/pmol) | |
| ALDH1A1 | 1.1 ± 0.1 | 285 ± 24 | 3.9 | 3.0 ± 2.2 | 7,434 ± 6,700 | 1,468 ± 1,320 | 0.4 |
| ALDH1A2 | 3.7 ± 0.1 | 56 ± 5 | 66.1 | N/A | N/A | N/A | N/A |
| ALDH1A3 | 0.3 ± 0.01 | 261 ± 18 | 1.1 | N/A | N/A | N/A | N/A |
Clint, intrinsic clearance calculated as kcat/Km.
